|
KMID : 0355319920150010011
|
|
Journal of Korean Academy of Oral Pathology
1992 Volume.15 No. 1 p.11 ~ p.22
|
|
|
DEVELOPMENT OF THE ORAL CAVITY IN STAGED HUMAN EMBRYOS
|
|
1김진/1Jin Kim
2강윤선/3박형우/2Yun Seon Kang/3Hyoung Woo Park
|
|
|
Abstract
|
|
|
-Abstract-
To investigate the development of oral cavity according to the developmental stage of
human embryo, the serial sections of 20 human embryos, staged by Carnegie staging
system, were examined. Also the three-dimensional reconstruction models of head and
neck region were made of blotting papers and analyzed to study the positional
interrelationship of oral structures.
In stage 12, the oropharyngeal membrane had been ruptured, but its remnants were not
seen. The lumen was formed in the primordium of thyroid gland in stage 14, and the
gland appeared bilobed in stage 15. The primordium of tongue was observed in stage
15, with the appearance of the primordium of lingual muscles in stage 16 and lingual
papilla in stage 21. In stage 16, the tooth bud made its appearance in the form of
primary epithelial band, and the downward proliferation provided dental lamina in stage
20 and the cap stage structures in stage 23, respectively. Following the development of
Meckel's cartilage in stage 17, the development of mandible initiated as a blastema in
stage 18, of which the ossification appeared in stage 20, but the ossification of the
maxilla was found in stage 21. The epithelial invaginations for submandibular gland
were observed in stage 18, and developed to make branching in stage 21 and lumen
formation in stage 22. The primordium of sublingual gland appeared in stage 23. The
lateral palatal processes derived from maxillary process, were elongated in stage 18, but
the fusion did not occur until the late stage of 23.
Following the above results, the development of oral structures is assumed to be
interdependent process. The initial signal seemed to be transmitted from epithelium to
mesenchyme in the structures requiring epithelium-mesenchymal interation.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|